Strange Science: Ketamine For Treating Depression

Scientists have recently been studying the possible use of ketamine as a fast-acting treatment for depression, particularly major depressive disorder and bipolar depression.

Ketamine is predominantly used as a medication for starting and maintaining anesthesia, for humans and domestic animals. It has also been used as a recreational drug. But with low, subanesthetic doses, it may be effective in helping to treat depression quickly, rather than in the weeks that it can take some other depression medications to reach their full effect.

The review of these recent studies and another study appear in the Harvard Review of Psychiatry, but you can read a summary at Science Daily.

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Review of The Marauder’s Island by Tristan J. Tarwater

The Marauder’s Island by Tristan J. Tarwater (Back That Elf Up, 2016) is the first book in the Hen & Chick series. If you’re a fan of young adult stories with heart, action, adventure, and revenge, you’ll find plenty here and leave wanting more. The book follows the story of a young mage, Azria, who is reunited with her mother, a notorious pirate, who promised to return for her daughter when Azria was done with her mage training. Her mother’s ship, the Hen & Chick, is in need of a new mage for their ship. And while mages typically take care of somewhat mundane tasks on the ship like desalinating seawater for drinking purposes, Azria’s mother has a larger project in mind for her daughter–raising the fabled Marauder’s Island from where it was sunk many years ago by a very powerful mage.

The bulk of the story revolves around Azria and her mother, as they build the relationship that they have not previously had, but also work together as the captain of a ship and her mage. The many other characters on the Hen & Chick are diverse, and though you only get a small taste of most of these characters, it’s wonderful to see a largely non-white and predominately female ship crew. The book also includes tantalizing descriptions of the food that the characters eat that often left me curious about these dishes and their basis in real foods.

Though The Marauder’s Island is listed as the first book in the Hen & Chick series, there’s no indication of when to expect the next book. Needless to say, I’ll be anxiously awaiting its release!

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Battling in All Her Finery Submissions Now Open!

Battling in All Her FineryWe are now accepting submissions for Battling in All Her Finery. If you’ve got a first person tale of a woman leader of any kind, we’d love to see it! We’ll only be open until the end of March for this special call, and then we will reopen for regular submissions in June. Pay will be 2-cents per word. Check out more details on our submissions page!

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Permanent Exhibition

An essay by Mr. Vince DeMarsh, as provided by Dr. J. A. Grier
Art by America Jones


As an agent for eccentric artist-types, my life was unpredictable, but I had an eye for the kind of talent that made money. In fact, I was on the phone with some of that talent, and was getting more and more frustrated as the conversation continued. Trish was saying, “Vince you don’t understand. I can’t work. I mean it; it’s like my head is splitting open. I told you I’d be like this if it rained. I’m always like this when it rains.”

“You can’t take some aspirin?”

“No. Martin and I have tried absolutely every available treatment for my migraines and nothing works. Even the strongest prescription painkillers can’t cut through. We’ve tried acupuncture, homeopathy, supplements, allergy remedies, and all sorts of food intolerance tests. It’s making me nauseated just thinking about it. There is no solution other than waiting for the sun.”

“Given how much rain we’ve been having, I think that might not work.”

“I know. Listen. Bottom line is I might not have the paintings finished on time for the first exhibition.”

I got angry. “Trish, you are under contract–a very strict contract with substantial financial liability for both of us. You will fill that gallery show, and then the two shows afterwards, or neither of us will work in this city again.”

“Stop ranting; it’s making my head pound. I just need you to move the date by a week.”

“I can’t. We are locked in, both of us. So you absolutely will fill that gallery by opening night.” Then I softened my tone, thinking maybe that approach would be more effective. “Look. I know you have some older work. It’s not as fresh as your recent stuff, but between that and the pieces you’ve painted this spring I bet you can pull this together. Remember, this is the kind of opportunity that could make your career. Will make your career.” It would make–or break–my career, too, but I didn’t say that.

Here was a long pause. Finally, she said, “Okay. I will manage somehow. I’m not missing this for anything. Anything.”

She hung up.

The rain hardly quit for the next two weeks. I called every few days to get an update, but the only person answering her phone was her husband Martin. He kept assuring me that the paintings would be ready to go on schedule. I was concerned, but I knew that Trish was ambitious, driven, and tenacious. So I wasn’t too surprised when, at the critical point, there were indeed enough pieces to pull off a show.

It was thankfully good weather that night as patrons filed in to view Trish’s pieces. Trish stood by, pale but smiling, answering questions and avoiding me. I was working the crowd.  I always kept shows casual but classy, with a drink and a handshake for everyone through the door. I had a great memory for names and faces, too.

But the act was a struggle tonight. The art was good, but not as stunning as I’d hoped. I knew she was capable of a great deal more than this, which is why I had agreed to this gamble in the first place.

After all the patrons had left, I grabbed a bottle from the bar and poured myself another glass of wine. I went up to Trish and Martin. “Well, a passable opening here overall. A few pieces sold, but, Trish, this is not what I’ve come to expect from you.”

She frowned. “I’m more disappointed than you are, I guarantee it.”

“Maybe. If you sell a few more pieces over the next two weeks while the art is on display, then that will help. But the financial outlay for these three exhibitions is considerable, as you are well aware. Either we pack them in for the next two shows or we take a big loss. Your contract–”

Martin spoke, irritated with me. “Yes, we are well aware, Vince.”

I was not going to be derailed, and continued to address Trish. “Can you guarantee me a better second show?”

“If it stops raining, then yes.”

I turned to Martin. “There really is nothing you haven’t tried?”

“That’s right.”

I rubbed my chin then shrugged. “Well, it’s only our careers on the line. Let me know if there is anything I can do between now and July.”

They both gave me a sour look. Martin said, “Find a cure for migraines.”

With that, we went our own ways. For a week it was fine, the sun was shining and reports from Trish were that she was working pretty steadily, and she liked the results.

Then it started raining again.

Art for "Permanent Exhibition"

Trish was smiling. “It is dangerous. It is very addictive. I need more.”


To read the rest of this story, check out the Mad Scientist Journal: Winter 2018 collection.


Mr. Vince DeMarsh is the highly successful CEO of the DeMarsh Agency, representing the finest artists in the metropolitan area. His most famous client, artist Trish Randall, has received rave reviews for her latest exhibition of paintings around the theme “The Consuming Fire.”


Dr. J. A. Grier is a planetary scientist, poet, fiction writer, and wine lover. Her stories and poems have appeared in venues such as Mad Scientist Journal, Eye to the Telescope, Liquid Imagination, and Mirror Dance. She is a member of the Horror Writers Association and the Science Fiction and Fantasy Poetry Association. Dr. Grier spends her time penning odd articles, reading strange stories, comparing vintages, and looking at impact craters on other worlds. She throws a fabulous Halloween party every year where one room is decorated entirely in eyeballs. Her babblings can be found at jagrier.com and @grierja on Twitter.


AJ is an illustrator and comic artist with a passion for neon colors and queer culture. Catch them being antisocial on social media @thehauntedboy.


“Permanent Exhibition” is © 2017 J. A. Grier
Art accompanying story is © 2017 America Jones

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Strange Science: Math and Probability

Math and probability are fascinating topics, which not everyone enjoy. But for those who are fans of these things, there are all sorts of unusual facts in these fields. This article lists ten of the most surprising math facts.

Of them, the Birthday Paradox was a familiar one, though we’re still not sure how it works. It would make sense that if you have 367 people in a room, at least two of them would have the same birthday. But if you have only 23 people in a room, there’s a 50% chance that two of them will share a birthday! (Interestingly, though, co-editor Dawn works in an office with a total of 14 people, and there are three sets of “birthday twins” in her office, all in July and August!)

But the idea that there are different levels or sizes of infinity is pretty mind blowing for someone who is not a mathematician. We’d always thought that infinity was just uncountable. It seems that in reality, it’s much more than that!

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Battling in All Her Finery Kickstarter Concludes Tonight!

Battling in All Her FineryWe’ve reached the final day for our Kickstarter for Battling in All Her Finery! If you’d like to celebrate with us, pop over to our Facebook event tonight at 7 p.m. Pacific time, for a livestream with our herd of Feline Interns!

Also if you’ve backed our Kickstarter, are you also a backer on our Patreon? Folks who back in both locations get special perks–postcards featuring the interior artwork if you back the Kickstarter at any level, and a fancy bookplate signed by the editors if you back at any level that includes a physical book! The Patreon is also a great way to subscribe to the quarterly Mad Scientist Journal. You can check it out here!

Tomorrow, we’ll open to submissions for stories for Battling in All Her Finery. You can find the guidelines here, and the submission portal (which is different from our usual submission portal) will be here.

And finally, if you were waiting until the last minute to back, it’s here. It’s the last minute! Here’s the link to the Kickstarter!

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That Man Behind the Curtain: January 2018

Our table at Foolscap 2018!

Our table at Foolscap 2018!

January saw the final steps towards launching this month’s Kickstarter, so some of the expenses reflect that.

The Money Aspect

Amounts in parentheses are losses/expenses.
Web Resources: (-$67.06)
Stories: (-$260.00)
Art: (-$684.00)
Advertising: (-$85.43)
Processing Fees: (-$18.39)
Printing: (-$21.59)
Donations: $44.71
Ad Revenue: $0.25
Online Book Sales: $88.57

Total: (-$1,002.94)
QTD: (-$2,094.45)
YTD: (-$4,188.90)
All Time: (-$27,926.83)

As usual, I try to list costs for art and stories under the month that the stories run on the site rather than when I pay them. (This does not apply to special content for quarterlies, which does not have a specific month associated with it.) Sales are for sales when they take place, not when they’re actually paid out to me. Online book sales reflect the royalties given after the retailer takes their cut. Physical book sales represent gross income, not counting the cost of the physical book. Donations include Patreon as well as other money sent to us outside of standard sales.

The huge spike in art was payment for both our Kickstarter book cover as well as our quarterly book cover.

I finally broke down and pulled our banner ads. After six years of getting 50-cents a month, I decided that it was just too ridiculous a failure to keep hoping will succeed.

Submissions

We were closed to submissions in January. Our all time acceptance rate is remains 37.9%.

Followers

Below is the social media following we had at the end of January. It is perhaps worth noting that for the money part, I record when we get the funds from Patreon at the beginning of the month. Here we have the number of backers at the end of the month. So we had a drop off in backers between the patrons being charged and the end of the month. It was offset by some new patrons, but still a net loss.

Patreon: 13 (-1)

Facebook: 1,774 (+24)

Twitter: 574 (+4)

Tumblr: 286 (+7)

Mailing List: 96 (+10)

Google+: 63 (+0)

Traffic

Last three months:

January 2018: 1,650 visits, 1,251 users, 2,534 page views, peak day of 73.
December 2017: 1,441 visits, 1,077 users, 2,419 page views, peak day of 84.
November 2017: 1,491 visits, 1,137 users, 2,108 page views, peak day of 121.

Last three Januarys:

January 2017: 867 visits, 662 users, 1,537 pages views, peak day of 48 visits.
January 2016: 1,601 visits, 979 users, 3,270 page views, peak day of 94 visits.
January 2015: 2,063 visits, 1,400 users, 3,740 page views, peak day of 172 visits.

Traffic is continuing apace from last month. The previous Januarys appear to be outliers in our traffic patterns, but we think it’s because we started our 2016 Kickstarter in mid-January, and we were open to submissions in January 2015.

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Lucky Stars

An essay by Pat Delmarre, as provided by Robert Dawson
Art by Scarlett O’Hairdye


“Don’t you ever feel guilty?” I asked Brianna.

“Naaah.” She tapped her nails, hot pink with black Klingon alphabet decals, nervously on the arm of the couch. “And if I do, I just think about that Venge bicycle I’ll be riding next week. Twenty thousand smackeroos, including the custom respray. And that’s just the beginning.” She smiled luxuriantly, and took another big handful of chips. “What are you planning to do with yours, Pat?”

“I haven’t really thought beyond paying off my student loan,” I confessed. “Maybe a BMW convertible or something.”

“Well, better start thinking, kiddo. In an hour, we’re going to be rich. Probably.”

We’d been working on it for almost a year.

Brianna and I had been not-quite-making-out on the couch, with the evening news ignored in the background. I was stroking the smooth skin of her upper arm, making slow progress towards more interesting places, when suddenly she grasped my hand and pulled it firmly away from her.

“Aw, Bri–don’t be like that.”

“It’s OK, Pat. Just listen to this first.” She pointed with her other hand towards the TV.

“I don’t get it. Nobody won the lottery: what kind of a story is that?”

“Yeah, but did you see how big the next jackpot will be? Thirty million dollars.”

“That happens a lot more since they stopped paying small prizes and put it all onto one big one.”

“Yes, but don’t you see? With a lottery like this one, six numbers out of forty-nine in any order, there are only fourteen million combinations. So with two-dollar tickets, the expected value of each ticket is more than the cost. There’s got to be an angle on this.” She got her Genius At Work look.

“Yeah,” I said. “Only if you won the jackpot, with this many people buying tickets, you’d probably have to share it. There goes your edge.” I tried to wriggle my hand free.

She held on firmly. “Pat. It’s rolled over for five weeks in a row. What does that tell you?”

“Errrh, nobody bet on the winning numbers?”

“Smarty-pants. But we know there’s a bazillion people buying tickets, so they must all be clustering on other numbers.”

“Why?”

“Grandchildren’s birthdays, 1-2-3-4-5-6, things like that. They’re just as likely to win, of course, but if they do, they’ll have to share. I bet if we bought enough tickets on the boring numbers, we’d have a good investment.”

“No way.”

“Way. Voltaire and Le Condamine did something like it in the eighteenth century. I learned about it in my history of math class.”

“Bri, maybe this Condom guy had fourteen million dollars to invest, but I don’t, even if the odds are good. You don’t either.”

“Right. So we get partners. You find ways of doing that, that’s what your B.Comm. courses are there for. Me, I’ll work on herding the sheep a bit tighter. Improve our odds.” She grinned and put my hand back, about where it had been before the interruption. “Now, where were we?” I did not answer; Brianna’s lips were in the way.

Art for "Lucky Stars"

She put it online, and charged ninety-nine cents. For that, she promised free upgrades–any time she wrote a new selection algorithm, everybody would get it automatically, without even having to ask. Within a few days, orders were flooding in.


To read the rest of this story, check out the Mad Scientist Journal: Winter 2018 collection.


Pat Delmarre has a B.Comm., three jobs, and a humongous student debt. Like Mount Everest sized? Pat lives with Brianna Flick, provided that Brianna does not have any more so-called clever ideas. Ever. Because eating Kraft Dinner every day is getting totally boring.


Robert Dawson has a Ph.D., teaches mathematics at a Nova Scotian University, and writes science fiction. He has taught probability theory many times, and has never bought a lottery ticket. These two facts may be connected.


Scarlett O’Hairdye is a burlesque performer, producer and artist. To learn more, visit her site at www.scarlettohairdye.com.


“Lucky Stars” is © 2014 Robert Dawson
Art accompanying story is © 2017 Scarlett O’Hairdye


This story originally appeared in the October 2014 issue of Perihelion.

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Strange Science: Plants Under Sedation

We know that plants are alive, but did you know that they can be sedated with the same drugs used to sedate humans?

Scientists have recently published a study in the Annals of Botany that details their experiments on the effects of a variety of drugs on pea plants. “Under anesthetics, the physical properties of cell membranes change, becoming more flexible. Apply pressure to the cells, this effect is reversed and the anesthetic wears off.” Because the membranes are associated with electrical signals within plants, the implications of their study suggest that much like the electrical signals in human brains that are a part of human consciousness, so too might the changes in the membranes indicate a consciousness in plants.

You can read more about this phenomenon at the New York Times, or in the original article in Annals of Botany.

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Battling In All Her Finery is Funded!

Battling in All Her FineryOur Kickstarter for Battling in All Her Finery is now fully funded, and still chugging along toward some possible stretch goals! We’re looking forward to  telling folks about our open submission period and guidelines! So if you’re a writer, and you’ve got some ideas about women leaders, keep an eye on this space, as we’ll announce the submissions guidelines here.

In the meantime, tell all of your friends about the Kickstarter! The more, the merrier!

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